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Effectiveness and Implementation Trials to Address Mental Health in Type 1 Diabetes

Deadlines are 5:00 PM (Eastern). No extensions will be granted.

Milestone Date Status
Letter of Intent Required Dec 18, 2023 Passed
Application Feb 20, 2024 Passed
Award Notification Jul 31, 2024 Next
Earliest Start Sep 01, 2024

Background & Purpose

Please click on the “RFA Announcement” link above for complete information.


JDRF aims to support the implementation and integration of evidence based T1D specific behavioral and psychosocial interventions into clinical practice. Therefore, JDRF solicits applications for studies and clinical trials designed to test psychosocial treatment and preventive interventions for which there is already evidence of efficacy, for use in community and practice settings.

This RFA will support clinical trials of interventions that already have feasibility, acceptability and efficacy data and are ready to go onto effectiveness and implementation trials. Projects may also only have feasibility and acceptability data and seek to utilize novel trial protocols with hybrid designs with emphasis on effectiveness and implementation outcomes.

Applications might include research to evaluate the effectiveness or increase the clinical impact of behavioral and psychosocial interventions to prevent or treat diabetes distress, anxiety, depression and/or disordered eating in T1D. Projects around provider-, organizational-, or systems-level interventions to improve access, continuity, and quality will also be considered.

LOIs should clearly describe the intervention, the preliminary data including efficacy data and, if available, data on mediators and moderators, and define the population to be studied, including mental health issue, age, and other characteristics.

Proposals should take an implementation focused approach to intervention development and testing, acknowledging that many people with T1D will receive care from providers unaffiliated with specialty diabetes or specialty psychological centers. The goal is to ensure that the resultant interventions are scalable and implementable in clinical care.

Informational Webinar and Q&A

JDRF will hold an announcement introduction meeting via Zoom on October 20, 2023, from 9-10 am Eastern Time to which all prospective applicants are invited. JDRF scientist(s) will give an overview of the goals of this initiative, explain the application process, and answer initial questions on applications.

Registration for Webinar (please register by October 19, 2023):